research suggests that N-nitrosamines and
nitrosamides be further investigated due
to their very high carcinogenic potency.
Based on these findings, the Foundation
has funded a follow-up project #4089,
“Method Development for Disinfection
By-Products Associated With Bladder
Cancer,” with the objective to develop
sensitive and reliable analytical tools to
confirm the formation and occurrence of
the target DBPs.
Epidemiological studies with meaningful
exposure assessment are needed to resolve
the question of health effects, however the
chemical(s) or mixture to which we must
measure exposure have not been identified.
In addition, DBP formation is influenced
by water parameters and while several
hundred DBPs have been identified, many
more remain unknown. As different classes
of DBPs may be formed from different
organic precursors, additional information
is needed to aid in future exposure
download free copies
of most Foundation
reports from the
Web site at www.
may also request free
printed reports by
Customer Service by
+ 1 888.844.5082 or
by e-mail to rfreports@